Reconstitution Calculator Equation

How to Use the Calculator

1. Enter the initial concentration of your solution in mg/mL.
2. Enter the initial volume of your solution in mL.
3. Enter the desired final concentration of your solution in mg/mL.
4. Click the "Calculate" button to determine the final volume and total solvent needed.

Working Principle

The calculator uses the formula C₁V₁ = C₂V₂, where:

• C₁ = Initial Concentration (mg/mL)
• V₁ = Initial Volume (mL)
• C₂ = Desired Final Concentration (mg/mL)
• V₂ = Final Volume (mL)

The final volume (V₂) is calculated by multiplying the initial concentration (C₁) by the initial volume (V₁) and then dividing by the desired final concentration (C₂). The total solvent needed is the difference between the final volume and the initial volume.

Example

If you have 10 mg/mL of a solution in 50 mL, and you want to reconstitute it to a final concentration of 5 mg/mL, the calculator will determine that you need to add 100 mL of solvent to achieve the desired concentration.