Osmolal Gap Calculator

Osmolal Gap Calculator calculator can be used to estimate the osmolal gap in the blood, which is a measure of the difference between the measured osmolality of blood and the calculated osmolality based on measured glucose, urea, and electrolytes.

Input Parameters

Calculation Results

Calculation Formula

Osmolal Gap = 2 * (Sodium + Potassium) - (Glucose/18 + Urea/2.8 + Chloride)

Where:
Glucose is in mg/dL
Urea is in mg/dL
Sodium, Potassium, and Chloride are in mEq/L
18 is the conversion factor for glucose to osmolality
2.8 is the conversion factor for urea to osmolality

Result

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Osmolal Gap Calculator Calculator Usage Guide

Learn how to use the Osmolal Gap Calculator calculator and its working principles

How to Use the Calculator

The Osmolal Gap Calculator estimates the osmolal gap in the blood, which is a measure of the difference between the measured osmolality of blood and the calculated osmolality based on measured glucose, urea, and electrolytes. To use the calculator, follow these steps:

  1. Enter the value for Glucose in mg/dL.
  2. Enter the value for Urea in mg/dL.
  3. Enter the value for Sodium in mEq/L.
  4. Enter the value for Potassium in mEq/L.
  5. Enter the value for Chloride in mEq/L.
  6. Click the "Calculate" button to compute the osmolal gap.
  7. The result will be displayed in the "Result" section.

Understanding the Osmolal Gap

The osmolal gap is calculated using the formula:

Osmolal Gap = 2 * (Sodium + Potassium) - (Glucose/18 + Urea/2.8 + Chloride)

A normal osmolal gap is typically less than 10 mOsm/kg. An elevated osmolal gap may indicate the presence of unmeasured osmotically active particles in the blood, such as ethanol, methanol, or ethylene glycol.