Total Daily Osmolar Output Calculator

Calculate the total daily osmolar output in a patient, which is important for assessing kidney function and fluid balance

Input Parameters

Calculation Results

Calculation Formula

TDO = (Urine Volume × [Na+]) + (Urine Volume × [Cl-]) + (Urine Volume × [Urea]) + (Urine Volume × [Glucose]) + (Urine Volume × [Ca2+])

Where:
TDO = Total Daily Osmolar Output (mOsm/kg/day)
Urine Volume = Volume of urine produced in 24 hours (mL/day)
Na+ = Sodium concentration in urine (mEq/L)
Cl- = Chloride concentration in urine (mEq/L)
Urea = Urea concentration in urine (mEq/L)
Glucose = Glucose concentration in urine (mEq/L)
Ca2+ = Calcium concentration in urine (mEq/L)

Total Daily Osmolar Output Calculator Calculator Usage Guide

Learn how to use the Total Daily Osmolar Output Calculator and its working principles

How to Use the Calculator

  1. Enter the urine volume in milliliters per day (mL/day).
  2. Enter the concentration of sodium in milliequivalents per liter (mEq/L).
  3. Enter the concentration of chloride in milliequivalents per liter (mEq/L).
  4. Enter the concentration of urea in milliequivalents per liter (mEq/L).
  5. Enter the concentration of glucose in milliequivalents per liter (mEq/L).
  6. Enter the concentration of calcium in milliequivalents per liter (mEq/L).
  7. Click the "Calculate" button to compute the total daily osmolar output.
  8. The result will be displayed in milliosmoles per day (mOsm/day).

Understanding Total Daily Osmolar Output

Total Daily Osmolar Output (TDO) is a measure of the total number of osmoles excreted in the urine over a 24-hour period. It is an important parameter in assessing kidney function and fluid balance.

Interpreting Results

A normal TDO range is typically between 500-1000 mOsm/day. Values outside this range may indicate dehydration, overhydration, or kidney dysfunction.

Principle of Calculation

The calculator uses the following formula to calculate TDO:

TDO = (Urine Volume × [Na+]) + (Urine Volume × [Cl-]) + (Urine Volume × [Urea]) + (Urine Volume × [Glucose]) + (Urine Volume × [Ca2+])