MDRD Calculator

MDRD Calculator calculator can be used to estimate the glomerular filtration rate (GFR) based on serum creatinine, age, sex, and race.

Input Parameters

Calculation Results

Calculation Formula

GFR (mL/min/1.73m²) = 186 × (SCr)⁻¹.154 × (Age)⁻⁰.203 × (Sex factor) × (Race factor)

Where:
GFR = Glomerular Filtration Rate
SCr = Serum Creatinine
Age = Age in years
Sex factor = 1.0 for males, 0.738 for females
Race factor = 1.212 for African Americans, 0.676 for Caucasians, 0.725 for Asians, 0.603 for Other

MDRD Calculator Calculator Usage Guide

Learn how to use the MDRD Calculator calculator and its working principles

How to Use the MDRD Calculator

  1. Enter the patient's serum creatinine level in mg/dL.
  2. Input the patient's age in years.
  3. Select the patient's sex (Male or Female).
  4. Choose the patient's race from the dropdown menu (Caucasian, African American, Asian, or Other).
  5. Click the "Calculate" button to estimate the GFR.
  6. The estimated GFR value will be displayed in mL/min/1.73m².

Understanding the MDRD Formula

The MDRD equation is used to estimate the glomerular filtration rate (GFR) based on serum creatinine, age, sex, and race. The formula is:

GFR (mL/min/1.73m²) = 186 × (SCr)⁻¹.154 × (Age)⁻⁰.203 × (Sex factor) × (Race factor)

The race factor adjusts the GFR estimate based on racial differences in creatinine production and elimination. The formula was developed primarily using data from Caucasian and African American patients, so caution should be used when applying it to other racial groups.

Interpreting the Results

The estimated GFR helps healthcare providers assess kidney function and stage chronic kidney disease (CKD). The National Kidney Foundation (NKF) stages CKD based on GFR:

  • Stage 1: GFR ≥ 90 mL/min/1.73m²
  • Stage 2: GFR 60-89 mL/min/1.73m²
  • Stage 3: GFR 30-59 mL/min/1.73m²
  • Stage 4: GFR 15-29 mL/min/1.73m²
  • Stage 5: GFR < 15 mL/min/1.73m²

Note: This calculator provides an estimate of GFR and should be used as an aid in clinical decision-making. Always consult with a healthcare professional for proper diagnosis and treatment.