Total Daily Osmolar Output Calculator

This calculator helps in determining the total daily osmolar output which is useful in assessing kidney function and fluid balance in clinical settings.

Input Parameters

Calculation Results

Calculation Formula

TDO = (Urine Osmolality × Urine Volume) + (Serum Osmolality × 1000)

Where:
TDO = Total Daily Osmolar Output (mOsm/day)
Urine Osmolality = Urine osmolality in mOsm/kg
Urine Volume = Urine volume in mL/day
Serum Osmolality = Serum osmolality in mOsm/kg

Result

-- mOsm/day --

Enter values and click Calculate to see results

Total Daily Osmolar Output Calculator Usage Guide

Learn how to use the Total Daily Osmolar Output Calculator and its working principles

What is Total Daily Osmolar Output?

Total Daily Osmolar Output (TDO) is a measure that represents the total amount of osmotically active particles excreted in the urine per day. It helps in assessing kidney function, fluid balance, and can be useful in diagnosing certain conditions such as diabetes insipidus.

How to Use This Calculator

  1. Enter the Urine Osmolality in mOsm/kg (measured from a 24-hour urine sample)
  2. Enter the Urine Volume in mL/day (total volume of urine produced in 24 hours)
  3. Enter the Serum Osmolality in mOsm/kg (measured from blood sample)
  4. Click the "Calculate" button to compute the Total Daily Osmolar Output

Interpreting the Results

The normal range for Total Daily Osmolar Output is typically between 600-1000 mOsm/day, though this can vary based on individual clinical context. Values outside this range may indicate certain conditions that require medical attention.

Principle of Calculation

The calculator uses the following formula:

TDO = (Urine Osmolality × Urine Volume) + (Serum Osmolality × 1000)

This formula accounts for both the osmotic activity in the urine and the contribution from serum osmolality.