Reconstitution Calculator

How to Use the Reconstitution Calculator

1. Enter the concentration of your concentrated solution in mg/mL.
2. Enter the volume of the concentrated solution you will be using in mL.
3. Enter the desired concentration of your final reconstituted solution in mg/mL.
4. Click the "Calculate" button to determine the volume of diluent to add and the final volume of the reconstituted solution.
5. The calculator will display the amount of diluent (e.g., sterile water) to add and the final volume of the solution after reconstitution.

Principle of Calculation

The calculator uses the formula:

Final Volume = (Concentrated Volume × Concentrated Concentration) / Desired Concentration

Where the final volume is the total volume of the reconstituted solution, which equals the volume of the concentrated solution plus the volume of diluent added.

Example

If you have a 10 mg/mL vial of medication and you want to reconstitute it to a 2 mg/mL concentration, and you plan to use 5 mL of the concentrated solution:

Final Volume = (5 mL × 10 mg/mL) / 2 mg/mL = 25 mL

This means you need to add 20 mL of diluent (sterile water) to the 5 mL of concentrated solution to achieve a final volume of 25 mL with a concentration of 2 mg/mL.

Important Notes

• Always use the correct type of diluent as specified in the medication's package insert.
• Ensure that the final concentration is within the recommended range for the medication's intended use.
• When reconstituting medications, follow proper aseptic techniques to prevent contamination.
• This calculator provides general guidance and should not replace professional medical advice.